Sulforaphane Attenuates Gentamicin-Induced Nephrotoxicity: Role of Mitochondrial Protection
Sulforaphane (SFN), an isothiocyanate naturally occurring in Cruciferae, induces cytoprotection in several tissues. Its protective effect has been associated with its ability to induce cytoprotective enzymes through an Nrf2-dependent pathway. Gentamicin (GM) is a widely used antibiotic; nephrotoxici...
Main Authors: | Mario Negrette-Guzmán, Sara Huerta-Yepez, Omar Noel Medina-Campos, Zyanya Lucía Zatarain-Barrón, Rogelio Hernández-Pando, Ismael Torres, Edilia Tapia, José Pedraza-Chaverri |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2013-01-01
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Series: | Evidence-Based Complementary and Alternative Medicine |
Online Access: | http://dx.doi.org/10.1155/2013/135314 |
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