Evidence for a continuous drift of the HIV-1 species towards higher resistance to neutralizing antibodies over the course of the epidemic.

Evidence for a continuous drift of the HIV-1 species towards higher resistance to neutralizing antibodies over the course of the epidemic.

We compared the neutralization sensitivity of early/transmitted HIV-1 variants from patients infected by subtype B viruses at 3 periods of the epidemic (1987-1991, 1996-2000, 2006-2010). Infectious pseudotyped viruses expressing envelope glycoproteins representative of the viral quasi-species infect...

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Bibliographic Details
Main Authors: Mélanie Bouvin-Pley, Marion Morgand, Alain Moreau, Pauline Jestin, Claire Simonnet, Laurent Tran, Cécile Goujard, Laurence Meyer, Francis Barin, Martine Braibant
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23853594/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23853594/?tool=EBI

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