Integration of genomics, metagenomics, and metabolomics to identify interplay between susceptibility alleles and microbiota in adenoma initiation

Integration of genomics, metagenomics, and metabolomics to identify interplay between susceptibility alleles and microbiota in adenoma initiation

Abstract Background Colorectal cancer (CRC) is a multifactorial disease resulting from both genetic predisposition and environmental factors including the gut microbiota (GM), but deciphering the influence of genetic variants, environmental variables, and interactions with the GM is exceedingly diff...

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Bibliographic Details
Main Authors: Jacob E. Moskowitz, Anthony G. Doran, Zhentian Lei, Susheel B. Busi, Marcia L. Hart, Craig L. Franklin, Lloyd W. Sumner, Thomas M. Keane, James M. Amos-Landgraf
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Cancer
Subjects:
Genetics
Gut microbiota
Colorectal cancer
Metabolomics
Apc
Min
Online Access:http://link.springer.com/article/10.1186/s12885-020-07007-9

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http://link.springer.com/article/10.1186/s12885-020-07007-9

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