Polymerase-tagged respiratory syncytial virus reveals a dynamic rearrangement of the ribonucleocapsid complex during infection.

The ribonucleocapsid complex of respiratory syncytial virus (RSV) is responsible for both viral mRNA transcription and viral replication during infection, though little is known about how this dual function is achieved. Here, we report the use of a recombinant RSV virus with a FLAG-tagged large poly...

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Bibliographic Details
Main Authors: Emmeline L Blanchard, Molly R Braun, Aaron W Lifland, Barbara Ludeke, Sarah L Noton, Daryll Vanover, Chiara Zurla, Rachel Fearns, Philip J Santangelo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008987