Ubiquitin Interacting Motifs: Duality Between Structured and Disordered Motifs

Ubiquitin is a small protein at the heart of many cellular processes, and several different protein domains are known to recognize and bind ubiquitin. A common motif for interaction with ubiquitin is the Ubiquitin Interacting Motif (UIM), characterized by a conserved sequence signature and often fou...

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Main Authors: Matteo Lambrughi, Emiliano Maiani, Burcu Aykac Fas, Gary S. Shaw, Birthe B. Kragelund, Kresten Lindorff-Larsen, Kaare Teilum, Gaetano Invernizzi, Elena Papaleo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.676235/full