Evaluation of Anticonvulsant Activity of Dual COX-2/5-LOX Inhibitor Darbufelon and Its Novel Analogues

Neuroinflammation is an integral part of epilepsy pathogenesis and other convulsive conditions, and non-steroidal anti-inflammatory drugs (NSAIDs) present a potent tool for the contemporary search and design of novel anticonvulsants. In the present paper, evaluation of the anticonvulsant activity of...

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Bibliographic Details
Main Authors: Mariia Mishchenko, Sergiy Shtrygol’, Andrii Lozynskyi, Semen Khomyak, Volodymyr Novikov, Olexandr Karpenko, Serhii Holota, Roman Lesyk
Format: Article
Language:English
Published: Österreichische Apotheker-Verlagsgesellschaft m. b. H. 2021-05-01
Series:Scientia Pharmaceutica
Subjects:
Online Access:https://www.mdpi.com/2218-0532/89/2/22