gRASping the redox lever to modulate cancer cell fate signaling

RAS proteins are critical regulators of signaling networks controlling diverse cellular functions such as cell proliferation and survival and its mutation are among the most powerful oncogenic drivers in human cancers. Despite intense efforts, direct RAS-targeting strategies remain elusive due to it...

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Bibliographic Details
Main Authors: Chuan Han Jonathan Foo, Shazib Pervaiz
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231718311558