Population Substructure Has Implications in Validating Next-Generation Cancer Genomics Studies with TCGA

Population Substructure Has Implications in Validating Next-Generation Cancer Genomics Studies with TCGA

In the era of large genetic and genomic datasets, it has become crucially important to validate results of individual studies using data from publicly available sources, such as The Cancer Genome Atlas (TCGA). However, how generalizable are results from either an independent or a large public datase...

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Bibliographic Details
Main Authors: Marina D. Miller, Eric J. Devor, Erin A. Salinas, Andreea M. Newtson, Michael J. Goodheart, Kimberly K. Leslie, Jesus Gonzalez-Bosquet
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
population substructure
genetic admixture
endometrial cancer
ovarian cancer
The Cancer Genome Atlas
Online Access:http://www.mdpi.com/1422-0067/20/5/1192

Internet

http://www.mdpi.com/1422-0067/20/5/1192

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