Integrating biomarkers across omic platforms: an approach to improve stratification of patients with indolent and aggressive prostate cancer

Integrating biomarkers across omic platforms: an approach to improve stratification of patients with indolent and aggressive prostate cancer

Classifying indolent prostate cancer represents a significant clinical challenge. We investigated whether integrating data from different omic platforms could identify a biomarker panel with improved performance compared to individual platforms alone. DNA methylation, transcripts, protein and glycos...

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Bibliographic Details
Main Authors: Keefe Murphy, Brendan T. Murphy, Susie Boyce, Louise Flynn, Sarah Gilgunn, Colm J. O'Rourke, Cathy Rooney, Henning Stöckmann, Anna L. Walsh, Stephen Finn, Richard J. O'Kennedy, John O'Leary, Stephen R. Pennington, Antoinette S. Perry, Pauline M. Rudd, Radka Saldova, Orla Sheils, Denis C. Shields, R. William Watson
Format: Article
Language:English
Published: Wiley 2018-09-01
Series:Molecular Oncology
Subjects:
biomarkers
indolent
integration
LASSO
omics
prostate cancer
Online Access:https://doi.org/10.1002/1878-0261.12348

Internet

https://doi.org/10.1002/1878-0261.12348

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