Contribution of the Defective <it>BRCA1</it>, <it>BRCA2 </it>and <it>CHEK2 </it>Genes to the Familial Aggregation of Breast Cancer: a Simulation Study Based on the Swedish Family-Cancer Database

<p>Abstract</p> <p>The known breast cancer susceptibility genes only account for 20% to 25% of the excess familial risk of the disease <abbrgrp><abbr bid="B1">1</abbr></abbrgrp>. The present study assessed the contribution of <it>BRCA1/2 <...

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Bibliographic Details
Main Authors: Bermejo Justo, Pérez Alfonso, Hemminki Kari
Format: Article
Language:English
Published: BMC 2004-11-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
Online Access:http://www.hccpjournal.com/content/2/4/185