Contribution of the Defective <it>BRCA1</it>, <it>BRCA2 </it>and <it>CHEK2 </it>Genes to the Familial Aggregation of Breast Cancer: a Simulation Study Based on the Swedish Family-Cancer Database
<p>Abstract</p> <p>The known breast cancer susceptibility genes only account for 20% to 25% of the excess familial risk of the disease <abbrgrp><abbr bid="B1">1</abbr></abbrgrp>. The present study assessed the contribution of <it>BRCA1/2 <...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2004-11-01
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Series: | Hereditary Cancer in Clinical Practice |
Subjects: | |
Online Access: | http://www.hccpjournal.com/content/2/4/185 |