Vesicles from different Trypanosoma cruzi strains trigger differential innate and chronic immune responses

Vesicles from different Trypanosoma cruzi strains trigger differential innate and chronic immune responses

Trypomastigote forms of Trypanosoma cruzi, the causative agent of Chagas Disease, shed extracellular vesicles (EVs) enriched with glycoproteins of the gp85/trans-sialidase (TS) superfamily and other α-galactosyl (α-Gal)-containing glycoconjugates, such as mucins. Here, purified vesicles from T. cruz...

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Bibliographic Details
Main Authors: Paula M. Nogueira, Kleber Ribeiro, Amanda C. O. Silveira, João H. Campos, Olindo A. Martins-Filho, Samantha R. Bela, Marco A. Campos, Natalia L. Pessoa, Walter Colli, Maria J. M. Alves, Rodrigo P. Soares, Ana Claudia Torrecilhas
Format: Article
Language:English
Published: Taylor & Francis Group 2015-11-01
Series:Journal of Extracellular Vesicles
Subjects:
Trypanosoma cruzi
extracellular vesicles
innate and chronic immunity
TLR2
α-galactosyl
Online Access:http://www.journalofextracellularvesicles.net/index.php/jev/article/view/28734/pdf_43

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http://www.journalofextracellularvesicles.net/index.php/jev/article/view/28734/pdf_43

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