Fetuin‐A aggravates lipotoxicity in podocytes via interleukin‐1 signaling

Abstract Sterile inflammation is considered critical in the pathogenesis of diabetic nephropathy (DN). Here we show that Fetuin‐A (FetA) or lipopolysaccharide (LPS) exacerbate palmitic acid‐induced podocyte death, which is associated with a strong induction of monocyte chemoattractant protein‐1 (MCP...

Full description

Bibliographic Details
Main Authors: Jana M. Orellana, Kapil Kampe, Friederike Schulze, Jonas Sieber, Andreas W. Jehle
Format: Article
Language:English
Published: Wiley 2017-05-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.13287