Multiple GPCR Functional Assays Based on Resonance Energy Transfer Sensors

Multiple GPCR Functional Assays Based on Resonance Energy Transfer Sensors

G protein-coupled receptors (GPCRs) represent one of the largest membrane protein families that participate in various physiological and pathological activities. Accumulating structural evidences have revealed how GPCR activation induces conformational changes to accommodate the downstream G protein...

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Bibliographic Details
Main Authors: Yiwei Zhou, Jiyong Meng, Chanjuan Xu, Jianfeng Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
GPCR
functional assay
G-protein
β-arrestin
dimerization
BRET
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.611443/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.611443/full

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