miR-22 Modulates Lenalidomide Activity by Counteracting MYC Addiction in Multiple Myeloma

miR-22 Modulates Lenalidomide Activity by Counteracting MYC Addiction in Multiple Myeloma

<i>Background:</i> MYC is a master regulator of multiple myeloma (MM) by orchestrating several pro-tumoral pathways, including reprograming of the miRNA transcriptome. MYC is also involved in the acquirement of resistance to anti-MM drugs, including immunomodulatory imide drugs (IMiDs)....

Full description

Bibliographic Details
Main Authors: Daniele Caracciolo, Caterina Riillo, Giada Juli, Francesca Scionti, Katia Todoerti, Nicoletta Polerà, Katia Grillone, Lucia Fiorillo, Mariamena Arbitrio, Maria Teresa Di Martino, Antonino Neri, Pierosandro Tagliaferri, Pierfrancesco Tassone
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
multiple myeloma
MYC
microRNA
miR-22
lenalidomide
NK cells
Online Access:https://www.mdpi.com/2072-6694/13/17/4365

Internet

https://www.mdpi.com/2072-6694/13/17/4365

Similar Items