Antithetic relationship of dietary arachidonic acid and eicosapentaenoic acid on eicosanoid production in vivo

Eicosanoids are oxidative derivatives of arachidonic acid. When produced in excessive amounts, many are proinflammatory and/or prothrombotic agents. N-3 polyunsaturated fatty acids (PUFA) have been used to attenuate tissue arachidonic acid (AA, 20:4 n-6) levels and thus modulate eicosanoid productio...

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Bibliographic Details
Main Authors: B Li, C Birdwell, J Whelan
Format: Article
Language:English
Published: Elsevier 1994-10-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520397820