Pathophysiology of Post Transplant Hypertension in Kidney Transplant: Focus on Calcineurin Inhibitors Induced Oxidative Stress and Renal Sodium Retention and Implications with RhoA/Rho Kinase Pathway

Pathophysiology of Post Transplant Hypertension in Kidney Transplant: Focus on Calcineurin Inhibitors Induced Oxidative Stress and Renal Sodium Retention and Implications with RhoA/Rho Kinase Pathway

Post-transplant hypertension is a common occurrence during treatment with calcineurin inhibitors (CNIs) in kidney transplant population. The pathogenesis of vasoconstriction induced by CNIs involves vascular tone alterations and kidney sodium transport regulation. Among the factors involved a key ro...

Full description

Bibliographic Details
Main Authors: Lorenzo A. Calò, Verdiana Ravarotto, Francesca Simioni, Elena Naso, Francesco Marchini, Luciana Bonfante, Lucrezia Furian, Paolo Rigotti
Format: Article
Language:English
Published: Karger Publishers 2017-10-01
Series:Kidney & Blood Pressure Research
Subjects:
Post transplant hypertension
Calcineurin inhibitors
Angiotensin II
Rho kinase
Oxidative stress
Gitelman’s syndrome
Sodium retention
Online Access:https://www.karger.com/Article/FullText/483023

Internet

https://www.karger.com/Article/FullText/483023

Similar Items