Francisella recognition by inflammasomes: differences between Mice and Men

Pathogen recognition by intracellular sensors involves the assembly of a caspase-1 activation machine termed the inflammasome. Intracellular pathogens like Francisella that gain access to the cytosolic detection systems are useful tools to uncover the details of caspase-1 activation events. This r...

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Bibliographic Details
Main Authors: Mikhail A Gavrilin, Mark D Wewers
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00011/full