Sequence homology at the breakpoint and clinical phenotype of mitochondrial DNA deletion syndromes.

Sequence homology at the breakpoint and clinical phenotype of mitochondrial DNA deletion syndromes.

Mitochondrial DNA (mtDNA) deletions are a common cause of mitochondrial disorders. Large mtDNA deletions can lead to a broad spectrum of clinical features with different age of onset, ranging from mild mitochondrial myopathies (MM), progressive external ophthalmoplegia (PEO), and Kearns-Sayre syndro...

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Bibliographic Details
Main Authors: Bekim Sadikovic, Jing Wang, Ayman W El-Hattab, Megan Landsverk, Ganka Douglas, Ellen K Brundage, William J Craigen, Eric S Schmitt, Lee-Jun C Wong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3004954?pdf=render

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http://europepmc.org/articles/PMC3004954?pdf=render

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