Hypoxia in vascular networks: a complex system approach to unravel the diabetic paradox.

In this work we model the extent of hypoxia in the diabetic retina as a function of the area affected by vessel disruption. We find two regimes that differ on the ratio between the area of disrupted vasculature and the area of tissue in hypoxia. In the first regime the hypoxia is localized in the vi...

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Bibliographic Details
Main Authors: Yérali Gandica, Tobias Schwarz, Orlando Oliveira, Rui D M Travasso
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4237512?pdf=render