S100A4 suppresses cancer stem cell proliferation via interaction with the IKK/NF-κB signaling pathway

S100A4 suppresses cancer stem cell proliferation via interaction with the IKK/NF-κB signaling pathway

Abstract Background Bladder cancer often recurs due to incomplete elimination of the cancer stem cells (CSCs). Therefore, new strategies targeting bladder CSCs are needed and the aim of this study was to investigate the effect of S100A4 on the proliferation capacity of MB49 bladder cancer stem cells...

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Bibliographic Details
Main Authors: Yongtong Zhu, Yao Zhou, Xuan Zhou, Yangchun Guo, Daxiong Huang, Jialin Zhang, Chunyan Wang, Longmei Cai
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Cancer
Subjects:
S100A4
Cancer stem cells
Proliferation
IKK
NF-κB
Online Access:http://link.springer.com/article/10.1186/s12885-018-4563-7

Internet

http://link.springer.com/article/10.1186/s12885-018-4563-7

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