A Novel Antiviral Target Structure Involved in the RNA Binding, Dimerization, and Nuclear Export Functions of the Influenza A Virus Nucleoprotein.

A Novel Antiviral Target Structure Involved in the RNA Binding, Dimerization, and Nuclear Export Functions of the Influenza A Virus Nucleoprotein.

Developing antiviral therapies for influenza A virus (IAV) infection is an ongoing process because of the rapid rate of antigenic mutation and the emergence of drug-resistant viruses. The ideal strategy is to develop drugs that target well-conserved, functionally restricted, and unique surface struc...

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Bibliographic Details
Main Authors: Michinori Kakisaka, Yutaka Sasaki, Kazunori Yamada, Yasumitsu Kondoh, Hirokazu Hikono, Hiroyuki Osada, Kentaro Tomii, Takehiko Saito, Yoko Aida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4519322?pdf=render

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http://europepmc.org/articles/PMC4519322?pdf=render

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