A Novel Antiviral Target Structure Involved in the RNA Binding, Dimerization, and Nuclear Export Functions of the Influenza A Virus Nucleoprotein.
Developing antiviral therapies for influenza A virus (IAV) infection is an ongoing process because of the rapid rate of antigenic mutation and the emergence of drug-resistant viruses. The ideal strategy is to develop drugs that target well-conserved, functionally restricted, and unique surface struc...
Main Authors: | Michinori Kakisaka, Yutaka Sasaki, Kazunori Yamada, Yasumitsu Kondoh, Hirokazu Hikono, Hiroyuki Osada, Kentaro Tomii, Takehiko Saito, Yoko Aida |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-07-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC4519322?pdf=render |
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