Identification of DNA-Methylated CpG Islands Associated With Gene Silencing in the Adult Body Tissues of the Ogye Chicken Using RNA-Seq and Reduced Representation Bisulfite Sequencing

Identification of DNA-Methylated CpG Islands Associated With Gene Silencing in the Adult Body Tissues of the Ogye Chicken Using RNA-Seq and Reduced Representation Bisulfite Sequencing

DNA methylation is an epigenetic mark that plays an essential role in regulating gene expression. CpG islands are DNA methylations regions in promoters known to regulate gene expression through transcriptional silencing of the corresponding gene. DNA methylation at CpG islands is crucial for gene ex...

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Bibliographic Details
Main Authors: Won-Jun Lim, Kyoung Hyoun Kim, Jae-Yoon Kim, Seongmun Jeong, Namshin Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Genetics
Subjects:
gene silencing
DNA methylation
RNA-seq
RRBS – reduced representation bisulfite sequencing
transcriptome
methylome
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00346/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2019.00346/full

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