Progressive Reduction in Mitochondrial Mass Is Triggered by Alterations in Mitochondrial Biogenesis and Dynamics in Chronic Kidney Disease Induced by 5/6 Nephrectomy

Progressive Reduction in Mitochondrial Mass Is Triggered by Alterations in Mitochondrial Biogenesis and Dynamics in Chronic Kidney Disease Induced by 5/6 Nephrectomy

The five-sixth nephrectomy (5/6Nx) model is widely used to study the mechanisms involved in chronic kidney disease (CKD) progression. Mitochondrial impairment is a critical mechanism that favors CKD progression. However, until now, there are no temporal studies of the change in mitochondrial biogene...

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Bibliographic Details
Main Authors: Rodrigo Prieto-Carrasco, Fernando E. García-Arroyo, Omar Emiliano Aparicio-Trejo, Pedro Rojas-Morales, Juan Carlos León-Contreras, Rogelio Hernández-Pando, Laura Gabriela Sánchez-Lozada, Edilia Tapia, José Pedraza-Chaverri
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Biology
Subjects:
chronic kidney disease
5/6 nephrectomy
mitochondrial biogenesis
dynamics
mitochondrial impairment
Online Access:https://www.mdpi.com/2079-7737/10/5/349

Internet

https://www.mdpi.com/2079-7737/10/5/349

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