Empirical evaluations of analytical issues arising from predicting HLA alleles using multiple SNPs

<p>Abstract</p> <p>Background</p> <p>Numerous immune-mediated diseases have been associated with the class I and II HLA genes located within the major histocompatibility complex (MHC) consisting of highly polymorphic alleles encoded by the HLA-A, -B, -C, -DRB1, -DQB1 an...

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Bibliographic Details
Main Authors: Hansen John A, Wang Hongwei, Li Shuying, Zhang Xinyi, Zhao Lue
Format: Article
Language:English
Published: BMC 2011-04-01
Series:BMC Genetics
Online Access:http://www.biomedcentral.com/1471-2156/12/39