The Hypoxia-Inducible Factor (HIF) pathway in adipocytes: The role of HIF-2 in adipose inflammation and hypertrophic cardiomyopathy

Under obese conditions, adipose tissue can become oxygen-deficient or hypoxic. Extensive work has been done using various diet-induced obesity models to demonstrate an important role of hypoxia-induced signaling in adipose tissue and its impact on adipose functions related to adipogenesis, insulin...

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Bibliographic Details
Main Authors: Zhong eYun, Qun eLin
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2015.00039/full