The Hypoxia-Inducible Factor (HIF) pathway in adipocytes: The role of HIF-2 in adipose inflammation and hypertrophic cardiomyopathy

The Hypoxia-Inducible Factor (HIF) pathway in adipocytes: The role of HIF-2 in adipose inflammation and hypertrophic cardiomyopathy

Under obese conditions, adipose tissue can become oxygen-deficient or hypoxic. Extensive work has been done using various diet-induced obesity models to demonstrate an important role of hypoxia-induced signaling in adipose tissue and its impact on adipose functions related to adipogenesis, insulin...

Full description

Bibliographic Details
Main Authors:	Zhong eYun, Qun eLin
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2015-03-01
Series:	Frontiers in Endocrinology
Subjects:	Heart Hypertrophy Obesity hypoxia cardiomyopathy Adipocyte
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fendo.2015.00039/full

Similar Items

Hypertrophic Cardiomyopathy
by: Polakit Teekakirikul, MD, et al.
Published: (2021-09-01)

Apple Flavonols Mitigate Adipocyte Inflammation and Promote Angiogenic Factors in LPS- and Cobalt Chloride-Stimulated Adipocytes, in Part by a Peroxisome Proliferator-Activated Receptor-γ-Dependent Mechanism
by: Danyelle M. Liddle, et al.
Published: (2020-05-01)

HIF1α/TET1 Pathway Mediates Hypoxia-Induced Adipocytokine Promoter Hypomethylation in Human Adipocytes
by: Mohamed M. Ali, et al.
Published: (2020-01-01)

Effect of hypertrophy on left ventricular diastolic function in patients with hypertrophic cardiomyopathy
by: Massimo Chiariello, et al.
Published: (2006-09-01)

Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
by: Saverio Cinti, et al.
Published: (2005-11-01)

Raspberry (Rubus idaeus L.) fruit extract decreases oxidation markers, improves lipid metabolism and reduces adipose tissue inflammation in hypertrophied 3T3-L1 adipocytes
by: Katarzyna Kowalska, et al.
Published: (2019-11-01)

Mitochondrial Dysfunction in Adipocytes as a Primary Cause of Adipose Tissue Inflammation
by: Chang-Yun Woo, et al.
Published: (2019-06-01)

A rare case of apical hypertrophic cardiomyopathy (AHCM)
by: Seyed Abbas Mirabbasi, et al.
Published: (2017-04-01)

Oxygen deprivation and the cellular response to hypoxia in adipocytes – perspectives on white and brown adipose tissues in obesity
by: P eTrayhurn, et al.
Published: (2015-02-01)

RARE CASES OF HYPERTROPHIC CARDIOMYOPATHY: VARIANTS AND CLINICAL OBSERVATIONS
by: V. Yu. Zimina, et al.
Published: (2015-09-01)

ANATOMIC AND MORPHOLOGICAL SIGNS OF A DIFFUSE-GENERALIZED HYPERTROPHIC CARDIOMYOPATHY
by: S. L. Dzemeshkevich, et al.
Published: (2015-05-01)

Inter-ventricular Septum Ablation for the Treatment of Hypertrophic Obstructive Cardiomyopathy
by: Yuejin Wu, MS, Shaobo Duan, MD, Luwen Liu, MS, Shuaiyang Wang, MS, Shuang Xu, MS, Liuwei Hao, BS, Lianzhong Zhang, MD
Published: (2020-12-01)

Adipocyte morphometric evaluation and angiogenesis in the omentum transposed to the breast: a preliminary study
by: Sirlei Santos Costa, et al.
Published: (2011-01-01)

Genetic analysis in hypertrophic cardiomyopathy
by: Kabaeva, Zhyldyz
Published: (2002)

Asymmetrical septal hypertrophy and hypertrophic cardiomyopathy in infant of diabetic mother: A reversible cardiomyopathy
by: Deepak Sharma, et al.
Published: (2016-01-01)

Peculiarities of expression of HIF-1Α and HIF-3Α in hypothalamus of Wistar rats under the influence of intermittent hypobaric hypoxia
by: A. V. Abramov, et al.
Published: (2017-08-01)

Hypoxia and HIF activation as a possible link between sepsis and thrombosis
by: Colin E. Evans
Published: (2019-08-01)

VHL and Hypoxia Signaling: Beyond HIF in Cancer
by: Jing Zhang, et al.
Published: (2018-03-01)

Unraveling an Unusual Phenocopy of Hypertrophic Cardiomyopathy: MELAS Syndrome
by: Anna B. Reid, et al.
Published: (2021-02-01)

DIFFERENTIAL DIAGNOSIS OF HYPERTROPHIC CARDIOMYOPATHY
by: I. V. Leontyeva
Published: (2017-06-01)

Associations among echocardiography, cardiac biomarkers, insulin metabolism, morphology, and inflammation in cats with asymptomatic hypertrophic cardiomyopathy
by: Ingrid vanHoek, et al.
Published: (2020-03-01)

Hypoxia/HIF Modulates Immune Responses
by: Yuling Chen, et al.
Published: (2021-03-01)

HIF-1, Metabolism, and Diabetes in the Embryonic and Adult Heart
by: Radka Cerychova, et al.
Published: (2018-08-01)

Hypoxia-Inducible Factor (HIF) in Ischemic Stroke and Neurodegenerative Disease
by: Elena V. Mitroshina, et al.
Published: (2021-07-01)

Transcriptome Analyses of Adipose Tissue Samples Identify EGFL6 as a Candidate Gene Involved in Obesity-Related Adipose Tissue Dysfunction in Children
by: Biemann, R., et al.
Published: (2022)

Transcriptome Analyses of Adipose Tissue Samples Identify EGFL6 as a Candidate Gene Involved in Obesity-Related Adipose Tissue Dysfunction in Children
by: Biemann, R., et al.
Published: (2022)

Loss of G protein pathway suppressor 2 in human adipocytes triggers lipid remodeling by upregulating ATP binding cassette subfamily G member 1
by: Serena Barilla, et al.
Published: (2020-12-01)

Hypoxia-induced chemoresistance in cancer cells: The role of not only HIF-1
by: Helena Doktorova, et al.
Published: (2015-06-01)

The role of Asprosin in patients with dilated cardiomyopathy
by: Ming-Shien Wen, et al.
Published: (2020-09-01)

Homocysteine promotes hepatic steatosis by activating the adipocyte lipolysis in a HIF1α-ERO1α-dependent oxidative stress manner
by: Yu Yan, et al.
Published: (2020-10-01)

Genetic determinants of clinical phenotype in hypertrophic cardiomyopathy
by: Lazar Velicki, et al.
Published: (2020-12-01)

A case of diagnosis of asymmetric apical hypertrophic cardiomyopathy of the left ventricle with intraventricular obstruction
by: E A Nelipa, et al.
Published: (2014-04-01)

GLA Gene Mutation in Hypertrophic Cardiomyopathy with a New Variant Description: Is it Fabry's Disease?
by: Ândrea Virgínia Chaves-Markman, et al.

Pathogenic Mechanisms of Hypertrophic Cardiomyopathy beyond Sarcomere Dysfunction
by: Chun Chou, et al.
Published: (2021-08-01)

Hypertrophy and Insulin Resistance of Epicardial Adipose Tissue Adipocytes: Association with the Coronary Artery Disease Severity
by: Natalia V. Naryzhnaya, et al.
Published: (2021-01-01)

Epigenetic crosstalk between hypoxia and tumor driven by HIF regulation
by: Tiansheng Li, et al.
Published: (2020-10-01)

Hypoxia, HIF, and Associated Signaling Networks in Chronic Kidney Disease
by: Jing Liu, et al.
Published: (2017-04-01)

HIF-1 transcription activity: HIF1A driven response in normoxia and in hypoxia
by: Flora Cimmino, et al.
Published: (2019-02-01)

Alcohol Septal Ablation in Patients with Hypertrophic Cardiomyopathy and Obesity
by: K. V. Rudenko, et al.
Published: (2019-05-01)

Overexpression of bHLH domain of HIF-1 failed to inhibit the HIF-1 transcriptional activity in hypoxia
by: Fatemeh Sadeghi, et al.
Published: (2020-06-01)