Functional alterations of myeloid cells during the course of Alzheimer’s disease

Functional alterations of myeloid cells during the course of Alzheimer’s disease

Abstract Background Neuroinflammation is a hallmark of neurodegenerative disease and a significant component of the pathology of Alzheimer’s disease (AD). Patients present with extensive microgliosis along with elevated pro-inflammatory signaling in the central nervous system and periphery. However,...

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Bibliographic Details
Main Authors: Aaron D. Thome, Alireza Faridar, David R. Beers, Jason R. Thonhoff, Weihua Zhao, Shixiang Wen, Belen Pascual, Joseph C. Masdeu, Stanley H. Appel
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Molecular Neurodegeneration
Subjects:
Alzheimer’s disease
Inflammation
Myeloid cells
Monocyte
Microglia
Myeloid-derived suppressor cells
Online Access:http://link.springer.com/article/10.1186/s13024-018-0293-1

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http://link.springer.com/article/10.1186/s13024-018-0293-1

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