The dependence of expression of NF-κB-dependent genes: statistics and evolutionary conservation of control sequences in the promoter and in the 3′ UTR

<p>Abstract</p> <p>Background</p> <p>The NF-κB family plays a prominent role in the innate immune response, cell cycle activation or cell apoptosis. Upon stimulation by pathogen-associated patterns, such as viral RNA a kinase cascade is activated, which strips the NF-κB...

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Bibliographic Details
Main Authors: Iwanaszko Marta, Brasier Allan R, Kimmel Marek
Format: Article
Language:English
Published: BMC 2012-05-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/13/182