Functional Polymorphism in the NFE2L2 Gene Associated With Tuberculosis Susceptibility

Functional Polymorphism in the NFE2L2 Gene Associated With Tuberculosis Susceptibility

BackgroundNuclear transcription factor erythroid 2 p45-related factor 2 (Nrf2), encoded by NFE2L2, functions as a key transcription factor and regulates expression of antioxidant genes. Our study aimed to investigate the association of single nucleotide polymorphisms of NFE2L2 with tuberculosis (TB)...

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Bibliographic Details
Main Authors: Guiyi Ji, Miaomiao Zhang, Qianqian Liu, Shouquan Wu, Yu Wang, Guo Chen, Andrew J. Sandford, Jian-Qing He
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
NFE2L2
polymorphism
tuberculosis
latent tuberculosis infection
susceptibility
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.660384/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.660384/full

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