Towards the Development of AgoKirs: New Pharmacological Activators to Study K<sub>ir</sub>2.x Channel and Target Cardiac Disease

Towards the Development of AgoKirs: New Pharmacological Activators to Study K<sub>ir</sub>2.x Channel and Target Cardiac Disease

Inward rectifier potassium ion channels (I<sub>K1</sub>-channels) of the K<sub>ir</sub>2.x family are responsible for maintaining a stable negative resting membrane potential in excitable cells, but also play a role in processes of non-excitable tissues, such as bone developm...

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Bibliographic Details
Main Authors: Laura van der Schoor, Emma J. van Hattum, Sophie M. de Wilde, Netanja I. Harlianto, Aart-Jan van Weert, Meye Bloothooft, Marcel A. G. van der Heyden
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
inward rectifier channel
K<sub>ir</sub>2
agonist
I<sub>K1</sub>
Andersen syndrome
heart failure
Online Access:https://www.mdpi.com/1422-0067/21/16/5746

Internet

https://www.mdpi.com/1422-0067/21/16/5746

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