Role of the Mitochondrial Pyruvate Carrier in the Occurrence of Metabolic Inflexibility in <i>Drosophila melanogaster</i> Exposed to Dietary Sucrose

Role of the Mitochondrial Pyruvate Carrier in the Occurrence of Metabolic Inflexibility in <i>Drosophila melanogaster</i> Exposed to Dietary Sucrose

Excess dietary carbohydrates are linked to dysregulation of metabolic pathways converging to mitochondria and metabolic inflexibility. Here, we determined the role of the mitochondrial pyruvate carrier (MPC) in the occurrence of this metabolic inflexibility in wild-type (WT) and MPC1-deficient (MPC1...

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Bibliographic Details
Main Authors: Chloé J. Simard, Mohamed Touaibia, Eric Pierre Allain, Etienne Hebert-Chatelain, Nicolas Pichaud
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Metabolites
Subjects:
Drosophila
mitochondrial pyruvate carrier
mitochondrial respiration
homeostasis
sucrose
metabolomics
Online Access:https://www.mdpi.com/2218-1989/10/10/411

Internet

https://www.mdpi.com/2218-1989/10/10/411

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