Chemical-Genetic Interactions of <i>Bacopa monnieri</i> Constituents in Cells Deficient for the DNA Repair Endonuclease <i>RAD1</i> Appear Linked to Vacuolar Disruption

Chemical-Genetic Interactions of <i>Bacopa monnieri</i> Constituents in Cells Deficient for the DNA Repair Endonuclease <i>RAD1</i> Appear Linked to Vacuolar Disruption

Colorectal cancer is a common cancer worldwide and reduced expression of the DNA repair endonuclease XPF (xeroderma pigmentosum complementation group F) is associated with colorectal cancer. <i>Bacopa monnieri </i>extracts were previously found to exhibit chemical-genetic synthetic letha...

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Bibliographic Details
Main Authors: Chananya Huangteerakul, Hsu Mon Aung, Thitipa Thosapornvichai, Marisa Duangkaew, Amornrat Naranuntarat Jensen, Suchada Sukrong, Kornkanok Ingkaninan, Laran T. Jensen
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Molecules
Subjects:
<i>Bacopa monnieri</i>
colorectal cancer
synthetic lethality
chemical genetics
yeast
bacopasaponin C
Online Access:https://www.mdpi.com/1420-3049/26/5/1207

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https://www.mdpi.com/1420-3049/26/5/1207

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