The genome of the zoonotic malaria parasite Plasmodium simium reveals adaptations to host switching

The genome of the zoonotic malaria parasite Plasmodium simium reveals adaptations to host switching

Abstract Background Plasmodium simium, a malaria parasite of non-human primates (NHP), was recently shown to cause zoonotic infections in humans in Brazil. We sequenced the P. simium genome to investigate its evolutionary history and to identify any genetic adaptions that may underlie the ability of...

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Bibliographic Details
Main Authors: Tobias Mourier, Denise Anete Madureira de Alvarenga, Abhinav Kaushik, Anielle de Pina-Costa, Olga Douvropoulou, Qingtian Guan, Francisco J. Guzmán-Vega, Sarah Forrester, Filipe Vieira Santos de Abreu, Cesare Bianco Júnior, Julio Cesar de Souza Junior, Silvia Bahadian Moreira, Zelinda Maria Braga Hirano, Alcides Pissinatti, Maria de Fátima Ferreira-da-Cruz, Ricardo Lourenço de Oliveira, Stefan T. Arold, Daniel C. Jeffares, Patrícia Brasil, Cristiana Ferreira Alves de Brito, Richard Culleton, Cláudio Tadeu Daniel-Ribeiro, Arnab Pain
Format: Article
Language:English
Published: BMC 2021-10-01
Series:BMC Biology
Subjects:
Plasmodium simium
Plasmodium vivax
Malaria
Zoonosis
Comparative genomics
Online Access:https://doi.org/10.1186/s12915-021-01139-5

Internet

https://doi.org/10.1186/s12915-021-01139-5

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