New Anti-Cancer Strategy to Suppress Colorectal Cancer Growth Through Inhibition of ATG4B and Lysosome Function

Autophagy inhibition has been proposed to be a potential therapeutic strategy for cancer, however, few autophagy inhibitors have been developed. Recent studies have indicated that lysosome and autophagy related 4B cysteine peptidase (ATG4B) are two promising targets in autophagy for cancer therapy....

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Bibliographic Details
Main Authors: Yuanyuan Fu, Qianqian Gu, Li Luo, Jiecheng Xu, Yuping Luo, Fan Xia, Fanghai Han, Liang Hong, Xiao-Ming Yin, Zhiying Huang, Min Li
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/6/1523