Immune Dysregulation in Children With Down Syndrome

Immune Dysregulation in Children With Down Syndrome

Down syndrome (DS) is the most common genetic syndrome associated with immune defects. The extent of immune dysregulation in DS is substantial, spanning the innate and adaptive systems and including anomalies in: T and B cells, monocytes, neutrophil chemotaxis, circulating cytokines, and suboptimal...

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Bibliographic Details
Main Authors: Dean Huggard, Derek G. Doherty, Eleanor J. Molloy
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Pediatrics
Subjects:
Down syndrome
immune dysregulation
immunodeficiency
review
innate immunity
Online Access:https://www.frontiersin.org/article/10.3389/fped.2020.00073/full

Internet

https://www.frontiersin.org/article/10.3389/fped.2020.00073/full

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