Impact of Aging on the 6-OHDA-Induced Rat Model of Parkinson’s Disease

Impact of Aging on the 6-OHDA-Induced Rat Model of Parkinson’s Disease

Parkinson’s disease (PD) is the second most common age-related neurodegenerative disorder. The neurodegeneration leading to incapacitating motor abnormalities mainly occurs in the nigrostriatal pathway due to the loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc). Several anim...

Full description

Bibliographic Details
Main Authors: Sandra Barata-Antunes, Fábio G. Teixeira, Bárbara Mendes-Pinheiro, Ana V. Domingues, Helena Vilaça-Faria, Ana Marote, Deolinda Silva, Rui A. Sousa, António J. Salgado
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
Parkinson’s disease
aging
6-hydroxydopamine
animal model
neurodegeneration
Online Access:https://www.mdpi.com/1422-0067/21/10/3459

Internet

https://www.mdpi.com/1422-0067/21/10/3459

Similar Items