Sex differences in pharmacokinetics predict adverse drug reactions in women

Abstract Background Women experience adverse drug reactions, ADRs, nearly twice as often as men, yet the role of sex as a biological factor in the generation of ADRs is poorly understood. Most drugs currently in use were approved based on clinical trials conducted on men, so women may be overmedicat...

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Bibliographic Details
Main Authors: Irving Zucker, Brian J. Prendergast
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Biology of Sex Differences
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13293-020-00308-5