Robustness of Helicobacter pylori infection conferred by context-variable redundancy among cysteine-rich paralogs.

Deletion of single genes from expanded gene families in bacterial genomes often does not elicit a phenotype thus implying redundancy or functional non-essentiality of paralogous genes. The molecular mechanisms that facilitate evolutionary maintenance of such paralogs despite selective pressures agai...

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Bibliographic Details
Main Authors: Kalyani Putty, Sarah A Marcus, Peer R E Mittl, Lindsey E Bogadi, Allison M Hunter, Swathi Arur, Douglas E Berg, Palaniappan Sethu, Awdhesh Kalia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3608669?pdf=render