Distinct contributions of meprins to skin regeneration after injury – Meprin α a physiological processer of pro-collagen VII

Distinct contributions of meprins to skin regeneration after injury – Meprin α a physiological processer of pro-collagen VII

Astacin-like proteinases (ALPs) are regulators of tissue and extracellular matrix (ECM) homeostasis. They convey this property through their ability to convert ECM protein pro-forms to functional mature proteins and by regulating the bioavailability of growth factors that stimulate ECM synthesis. Th...

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Bibliographic Details
Main Authors: Daniel Kruppa, Florian Peters, Olivier Bornert, Mareike D. Maler, Stefan F. Martin, Christoph Becker-Pauly, Alexander Nyström
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Matrix Biology Plus
Subjects:
Wound healing
Extracellular matrix
Fibrosis
Inflammation
Dystrophic epidermolysis bullosa
Online Access:http://www.sciencedirect.com/science/article/pii/S2590028521000090

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http://www.sciencedirect.com/science/article/pii/S2590028521000090

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