A transcriptome-based signature of pathological angiogenesis predicts breast cancer patient survival.

The specific genes and molecules that drive physiological angiogenesis differ from those involved in pathological angiogenesis, suggesting distinct mechanisms for these seemingly related processes. Unveiling genes and pathways preferentially associated with pathologic angiogenesis is key to understa...

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Bibliographic Details
Main Authors: Rodrigo Guarischi-Sousa, Jhonatas S Monteiro, Lilian C Alecrim, Jussara S Michaloski, Laura B Cardeal, Elisa N Ferreira, Dirce M Carraro, Diana N Nunes, Emmanuel Dias-Neto, Jüri Reimand, Paul C Boutros, João C Setubal, Ricardo J Giordano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-12-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008482