Differences in MWCNT- and SWCNT-induced DNA methylation alterations in association with the nuclear deposition

Differences in MWCNT- and SWCNT-induced DNA methylation alterations in association with the nuclear deposition

Abstract Background Subtle DNA methylation alterations mediated by carbon nanotubes (CNTs) exposure might contribute to pathogenesis and disease susceptibility. It is known that both multi-walled carbon nanotubes (MWCNTs) and single-walled carbon nanotubes (SWCNTs) interact with nucleus. Such, nucle...

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Main Authors: Deniz Öner, Manosij Ghosh, Hannelore Bové, Matthieu Moisse, Bram Boeckx, Radu C. Duca, Katrien Poels, Katrien Luyts, Eveline Putzeys, Kirsten Van Landuydt, Jeroen AJ Vanoirbeek, Marcel Ameloot, Diether Lambrechts, Lode Godderis, Peter HM Hoet
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Particle and Fibre Toxicology
Subjects:
Carbon nanotubes
DNA methylation
Gene expression
Nuclear uptake
Toxicity
Epigenetics
Online Access:http://link.springer.com/article/10.1186/s12989-018-0244-6

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