Resistance to Immune Checkpoint Blockade in Uterine Leiomyosarcoma: What Can We Learn from Other Cancer Types?

by Wout De Wispelaere, Daniela Annibali, Sandra Tuyaerts, Diether Lambrechts, Frédéric Amant
Published 2021-04-01

VEGF receptor-2 (Flk-1) overexpression in mice counteracts focal epileptic seizures.

by Litsa Nikitidou, Irene Kanter-Schlifke, Joke Dhondt, Peter Carmeliet, Diether Lambrechts, Mérab Kokaia
Published 2012-01-01

Acriflavine Inhibits Acquired Drug Resistance by Blocking the Epithelial-to-Mesenchymal Transition and the Unfolded Protein Response

by Jeroen Dekervel, Ashenafi Bulle, Petra Windmolders, Diether Lambrechts, Eric Van Cutsem, Chris Verslype, Jos van Pelt
Published 2017-02-01

Loss of 1p36.33 Frequent in Low-Grade Serous Ovarian Cancer

by Els Van Nieuwenhuysen, Pieter Busschaert, Annouschka Laenen, Philippe Moerman, Sileny N. Han, Patrick Neven, Diether Lambrechts, Ignace Vergote
Published 2019-06-01

Induction and recovery of CpG site specific methylation changes in human bronchial cells after long-term exposure to carbon nanotubes and asbestos

by Deniz Öner, Manosij Ghosh, Robin Coorens, Hannelore Bové, Matthieu Moisse, Diether Lambrechts, Marcel Ameloot, Lode Godderis, Peter H.M. Hoet
Published 2020-04-01

A new protocol for single-cell RNA-seq reveals stochastic gene expression during lag phase in budding yeast

by Abbas Jariani, Lieselotte Vermeersch, Bram Cerulus, Gemma Perez-Samper, Karin Voordeckers, Thomas Van Brussel, Bernard Thienpont, Diether Lambrechts, Kevin J Verstrepen
Published 2020-05-01

Newborn genome-wide DNA methylation in association with pregnancy anxiety reveals a potential role for GABBR1

by Elise Beau Vangeel, Ehsan Pishva, Titia Hompes, Daniel van den Hove, Diether Lambrechts, Karel Allegaert, Kathleen Freson, Benedetta Izzi, Stephan Claes
Published 2017-10-01

Solar Lentigines are Associated with Better Outcome in Cutaneous Melanoma

by Vivien Marasigan, Canan Güvenç, Joost J. van den Oord, Marguerite Stas, Veerle Boecxstaens, Oliver Bechter, Pascal Wolter, Diether Lambrechts, Marjan Garmyn
Published 2019-09-01

Gemcitabine Recruits M2-Type Tumor-Associated Macrophages into the Stroma of Pancreatic Cancer

by Ashenafi Bulle, Jeroen Dekervel, Lise Deschuttere, David Nittner, Louis Libbrecht, Rekin's Janky, Stéphane Plaisance, Baki Topal, An Coosemans, Diether Lambrechts, Eric Van Cutsem, Chris Verslype, Jos van Pelt
Published 2020-03-01

RNA-sequencing in non-small cell lung cancer shows gene downregulation of therapeutic targets in tumor tissue compared to non-malignant lung tissue

by Kobe Reynders, Els Wauters, Matthieu Moisse, Herbert Decaluwé, Paul De Leyn, Stéphanie Peeters, Maarten Lambrecht, Kristiaan Nackaerts, Christophe Dooms, Wim Janssens, Johan Vansteenkiste, Diether Lambrechts, Dirk De Ruysscher
Published 2018-07-01

The footprint of the ageing stroma in older patients with breast cancer

by Barbara Brouwers, Debora Fumagalli, Sylvain Brohee, Sigrid Hatse, Olivier Govaere, Giuseppe Floris, Kathleen Van den Eynde, Yacine Bareche, Patrick Schöffski, Ann Smeets, Patrick Neven, Diether Lambrechts, Christos Sotiriou, Hans Wildiers
Published 2017-07-01

High-grade serous tubo-ovarian cancer refined with single-cell RNA sequencing: specific cell subtypes influence survival and determine molecular subtype classification

by Siel Olbrecht, Pieter Busschaert, Junbin Qian, Adriaan Vanderstichele, Liselore Loverix, Toon Van Gorp, Els Van Nieuwenhuysen, Sileny Han, Annick Van den Broeck, An Coosemans, Anne-Sophie Van Rompuy, Diether Lambrechts, Ignace Vergote
Published 2021-07-01

Methylation defect in imprinted genes detected in patients with an Albright's hereditary osteodystrophy like phenotype and platelet Gs hypofunction.

by Benedetta Izzi, Inge Francois, Veerle Labarque, Chantal Thys, Christine Wittevrongel, Koen Devriendt, Eric Legius, Annick Van den Bruel, Marc D'Hooghe, Diether Lambrechts, Francis de Zegher, Chris Van Geet, Kathleen Freson
Published 2012-01-01

Data describing the poor outcome associated with a breast cancer diagnosis in the post-weaning period

by Hanne Lefrère, Giuseppe Floris, Marjanka K. Schmidt, Patrick Neven, Ellen Warner, Elyce Cardonick, Fedro Alessandro Peccatori, Sibylle Loibl, Charlotte Maggen, Hanne De Mulder, Katarzyna J. Jerzak, Diether Lambrechts, Liesbeth Lenaerts, Frédéric Amant
Published 2021-10-01

Mismatch repair deficiency endows tumors with a unique mutation signature and sensitivity to DNA double-strand breaks

by Hui Zhao, Bernard Thienpont, Betül Tuba Yesilyurt, Matthieu Moisse, Joke Reumers, Lieve Coenegrachts, Xavier Sagaert, Stefanie Schrauwen, Dominiek Smeets, Gert Matthijs, Stein Aerts, Jan Cools, Alex Metcalf, Amanda Spurdle, ANECS, Frederic Amant, Diether Lambrechts
Published 2014-08-01

Phylogenetic reconstruction of breast cancer reveals two routes of metastatic dissemination associated with distinct clinical outcome

by David Venet, Danai Fimereli, Françoise Rothé, Bram Boeckx, Marion Maetens, Samira Majjaj, Ghizlane Rouas, Maria Capra, Giuseppina Bonizzi, Federica Contaldo, Christine Galant, Martine Piccart, Giancarlo Pruneri, Denis Larsimont, Diether Lambrechts, Christine Desmedt, Christos Sotiriou
Published 2020-06-01

Differences in MWCNT- and SWCNT-induced DNA methylation alterations in association with the nuclear deposition

by Deniz Öner, Manosij Ghosh, Hannelore Bové, Matthieu Moisse, Bram Boeckx, Radu C. Duca, Katrien Poels, Katrien Luyts, Eveline Putzeys, Kirsten Van Landuydt, Jeroen AJ Vanoirbeek, Marcel Ameloot, Diether Lambrechts, Lode Godderis, Peter HM Hoet
Published 2018-02-01

GLI2 promoter hypermethylation in saliva of children with a respiratory allergy

by Sabine A. S. Langie, Matthieu Moisse, Katarzyna Szarc vel Szic, Ellen Van Der Plas, Gudrun Koppen, Sofie De Prins, Tijs Louwies, Vera Nelen, Guy Van Camp, Diether Lambrechts, Greet Schoeters, Wim Vanden Berghe, Patrick De Boever
Published 2018-04-01

Variants in the 15q24/25 locus associate with lung function decline in active smokers.

by Firdaus A A Mohamed Hoesein, Els Wauters, Wim Janssens, Harry J M Groen, Joanna Smolonska, Cisca Wijmenga, Dirkje S Postma, H Marike Boezen, Pim A De Jong, Marc Decramer, Jan-Willem J Lammers, Diether Lambrechts, Pieter Zanen
Published 2013-01-01

MicroRNAs Possibly Involved in the Development of Bone Metastasis in Clear-Cell Renal Cell Carcinoma

by Lisa Kinget, Eduard Roussel, Diether Lambrechts, Bram Boeckx, Loïc Vanginderhuysen, Maarten Albersen, Cristina Rodríguez-Antona, Osvaldo Graña-Castro, Lucía Inglada-Pérez, Annelies Verbiest, Jessica Zucman-Rossi, Gabrielle Couchy, Stefano Caruso, Annouschka Laenen, Marcella Baldewijns, Benoit Beuselinck
Published 2021-03-01