Spheroid-Derived Cells From Renal Adenocarcinoma Have Low Telomerase Activity and High Stem-Like and Invasive Characteristics

Spheroid-Derived Cells From Renal Adenocarcinoma Have Low Telomerase Activity and High Stem-Like and Invasive Characteristics

Cancer stem cells (CSCs) are a theorized small subpopulation of cells within tumors thought to be responsible for metastasis, tumor development, disease progression, treatment-resistance, and recurrence. The identification, isolation, and biological characterization of CSCs may therefore facilitate...

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Bibliographic Details
Main Authors: Leili Saeednejad Zanjani, Zahra Madjd, Arezoo Rasti, Mojgan Asgari, Maryam Abolhasani, Kevin J. Tam, Raheleh Roudi, Gunhild Mari Mælandsmo, Øystein Fodstad, Yvonne Andersson
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Oncology
Subjects:
cancer stem cells
renal cell carcinoma
hTERT
telomerase activity
MST-312
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01302/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.01302/full

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