The combination of microfracture with induction of Wnt / β- Catenin pathway, leads to enhanced cartilage regeneration

The combination of microfracture with induction of Wnt / β- Catenin pathway, leads to enhanced cartilage regeneration

Abstract Introduction Microfracture does not lead to complete healing of full-thickness cartilage defects. The aim of this study was to evaluate the effect of modifying Wnt/β-catenin signaling following microfracture, on the restoration of a full-thickness cartilage defect in a rabbit model. The mod...

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Bibliographic Details
Main Authors: Nikitas P. Schizas, Olga Savvidou, Kalliopi Diamantopoulou, Stamatios Papadakis, Panayiotis J. Papagelopoulos, Ioannis K. Triantafyllopoulos
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Microfracture
Cartilage repair
Fibrocartilage
Wnt/β-catenin pathway
Lithium carbonate
Online Access:https://doi.org/10.1186/s13018-019-1484-3

Internet

https://doi.org/10.1186/s13018-019-1484-3

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