The IRF5 rs2004640 (G/T) polymorphism is not a genetic risk factor for systemic lupus erythematosus in population from south India

The IRF5 rs2004640 (G/T) polymorphism is not a genetic risk factor for systemic lupus erythematosus in population from south India

Background & objectives: Genetic aberrations disrupting toll-like receptor and interferon homeostasis enhance the risk of systemic lupus erythematosus (SLE). Raised serum interferon-alpha (IFN-α) levels in SLE patients have been ascribed to polymorphism (rs2004640 G/T) in interferon regulatory f...

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Bibliographic Details
Main Authors: Panneer Devaraju, Sonal Mehra, Reena Gulati, Paul T Antony, Vikramraj K Jain, Durga Prasanna Misra, Vir Singh Negi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Indian Journal of Medical Research
Subjects:
Autoantibodies - interferon-alpha - interferon regulatory factor 5 - polymorphism - systemic lupus erythematosus
Online Access:http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2018;volume=147;issue=6;spage=560;epage=566;aulast=

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http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2018;volume=147;issue=6;spage=560;epage=566;aulast=

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