SH3BGRL3 binds to myosin 1c in a calcium dependent manner and modulates migration in the MDA-MB-231 cell line

SH3BGRL3 binds to myosin 1c in a calcium dependent manner and modulates migration in the MDA-MB-231 cell line

Abstract Background The human SH3 domain Binding Glutamic acid Rich Like 3 (SH3BGRL3) gene is highly conserved in phylogeny and widely expressed in human tissues. However, its function is largely undetermined. The protein was found to be overexpressed in several tumors, and recent work suggested a p...

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Bibliographic Details
Main Authors: Filippo Di Pisa, Elisa Pesenti, Maria Bono, Andrea N. Mazzarello, Cinzia Bernardi, Michael P. Lisanti, Giovanni Renzone, Andrea Scaloni, Ermanno Ciccone, Franco Fais, Silvia Bruno, Paolo Scartezzini, Fabio Ghiotto
Format: Article
Language:English
Published: BMC 2021-08-01
Series:BMC Molecular and Cell Biology
Subjects:
SH3BGRL3
Myosin 1c
IQ domain
Cell migration
Online Access:https://doi.org/10.1186/s12860-021-00379-1

Internet

https://doi.org/10.1186/s12860-021-00379-1

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