Regulation of Constitutive Interferon-Stimulated Genes (Isgs) in Tumor Cells Contributes to Enhanced Antitumor Response of Newcastle Disease Virus-Infected Tumor Vaccines

Newcastle disease virus (NDV) is an oncolytic virus. As immunogenicity of tumor cells is enhanced by NDV infection, recombinant NDV-infected tumor vaccines (rNDV-TV) are effective methods for inducing specific immunity. However, several tumor cells resist NDV infection, and tumor specific immunity i...

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Bibliographic Details
Main Authors: Mai Takamura-Ishii, Takaaki Nakaya, Katsuro Hagiwara
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Cancers
Subjects:
ISG
Online Access:http://www.mdpi.com/2072-6694/10/6/186