Simultaneous molecular docking of different ligands to His6-tagged organophosphorus hydrolase as an effective tool for assessing their effect on the enzyme

Background Enzymatic hydrolysis of N-acyl homoserine lactones (AHLs), which are signaling molecules responsible for the development of antibiotic resistance in gram-negative bacteria, is a potential solution to overcoming antibiotic resistance problem. It has been established that hexahistidine-tagg...

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Bibliographic Details
Main Authors: Aysel Aslanli, Elena Efremenko
Format: Article
Language:English
Published: PeerJ Inc. 2019-09-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/7684.pdf