The complex interplay between endoplasmic reticulum stress and the NLRP3 inflammasome: a potential therapeutic target for inflammatory disorders

The complex interplay between endoplasmic reticulum stress and the NLRP3 inflammasome: a potential therapeutic target for inflammatory disorders

Abstract Inflammation is the result of a complex network of cellular and molecular interactions and mechanisms that facilitate immune protection against intrinsic and extrinsic stimuli, particularly pathogens, to maintain homeostasis and promote tissue healing. However, dysregulation in the immune s...

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Bibliographic Details
Main Authors: Wai Chin Chong, Madhur D Shastri, Gregory M Peterson, Rahul P Patel, Prabuddha S Pathinayake, Kamal Dua, Nicole G Hansbro, Alan C Hsu, Peter A Wark, Shakti Dhar Shukla, Matt D Johansen, Kate Schroder, Philip M Hansbro
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Clinical & Translational Immunology
Subjects:
endoplasmic reticulum stress
inflammasome
inflammatory disorder
NLRP3
Online Access:https://doi.org/10.1002/cti2.1247

Internet

https://doi.org/10.1002/cti2.1247

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